Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4343518 | 0.93 | FFAR1 (0.49) | FFAR1PTGDR2P2RX7NR3C2CARM1 | |
| SCHEMBL4337917 | 0.88 | NR3C2 (0.45) | PTGDR2NR3C2 | |
| SCHEMBL4328963 | 0.88 | PTGDR2 (0.47) | FFAR1PTGDR2NR3C2CARM1 | |
| SCHEMBL4342514 | 0.84 | ALDH1A1 (0.42) | FFAR1 | |
| SCHEMBL4334187 | 0.84 | FFAR1 (0.49) | FFAR1PTGDR2NR3C2 | |
| SCHEMBL4331854 | 0.84 | OPRM1 (0.44) | PTGDR2 | |
| SCHEMBL4334154 | 0.83 | LMNA (0.44) | FFAR1 | |
| SCHEMBL4335209 | 0.83 | PPARG (0.41) | PTPN7DUSP3P2RX7CARM1 | |
| SCHEMBL4335200 | 0.83 | PPARG (0.41) | PTPN7DUSP3P2RX7CARM1 | |
| SCHEMBL4334667 | 0.81 | NPC1 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |