Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342514 | 0.93 | ALDH1A1 (0.42) | LMNAPLAUALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4334667 | 0.90 | NPC1 (0.49) | LMNAKMT2APLAUALDH1A1L3MBTL1 | |
| SCHEMBL4328963 | 0.89 | PTGDR2 (0.47) | FFAR1 | |
| SCHEMBL4332643 | 0.88 | CASP1 (0.42) | LMNAPLAUALDH1A1CASP1CYP3A4 | |
| SCHEMBL4329062 | 0.86 | MAPT (0.48) | ALDH1A1L3MBTL1CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL4331854 | 0.86 | OPRM1 (0.44) | L3MBTL1MAPT | |
| SCHEMBL4339537 | 0.85 | HDAC1 (0.40) | PLAUALDH1A1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL4337917 | 0.85 | NR3C2 (0.45) | LMNAL3MBTL1BCHE | |
| SCHEMBL4335207 | 0.83 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL4343518 | 0.83 | FFAR1 (0.49) | ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |