Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328963 | 0.90 | PTGDR2 (0.47) | OPRM1PTGDR2 | |
| SCHEMBL4334667 | 0.89 | NPC1 (0.49) | MAPTL3MBTL1 | |
| SCHEMBL4334154 | 0.86 | LMNA (0.44) | MAPTL3MBTL1 | |
| SCHEMBL4337917 | 0.86 | NR3C2 (0.45) | MAPK14MMP12PTGDR2L3MBTL1 | |
| SCHEMBL4342514 | 0.85 | ALDH1A1 (0.42) | MAPT | |
| SCHEMBL4329062 | 0.85 | MAPT (0.48) | MAPTL3MBTL1 | |
| SCHEMBL4343518 | 0.84 | FFAR1 (0.49) | OPRM1PTGDR2PPARA | |
| SCHEMBL4335207 | 0.84 | FFAR1 (0.41) | PTGDR2 | |
| SCHEMBL4332643 | 0.83 | CASP1 (0.42) | MAPT | |
| SCHEMBL4328671 | 0.82 | PPARA (0.48) | HTR2CMAPK14MMP12EPHX2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| EP-1607103-A1 | CONCOMITANT DRUG AS THERAPEUTIC AGENT FOR INFLAMMATORY BOWEL DISEASE | Eisai Co., Ltd. (JP) | 2005-12-21 | — | — | EP | disclosed |