Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4328963 | 0.92 | PTGDR2 (0.47) | NR3C2PTGDR2 | |
| SCHEMBL4343518 | 0.88 | FFAR1 (0.49) | NR3C2KDM4EPTGDR2TACR1 | |
| SCHEMBL4334187 | 0.88 | FFAR1 (0.49) | NR3C2L3MBTL1BCHEKDM4ENPSR1 | |
| SCHEMBL4335207 | 0.88 | FFAR1 (0.41) | NR3C2PTGDR2 | |
| SCHEMBL4331854 | 0.86 | OPRM1 (0.44) | L3MBTL1MAPK14PTGDR2MMP12 | |
| SCHEMBL4334154 | 0.85 | LMNA (0.44) | L3MBTL1BCHELMNA | |
| SCHEMBL4342514 | 0.84 | ALDH1A1 (0.42) | LMNA | |
| SCHEMBL4343484 | 0.83 | PTGDR2 (0.45) | PTGDR2MMP1MMP12 | |
| SCHEMBL4334667 | 0.83 | NPC1 (0.49) | L3MBTL1KDM4ENPSR1LMNA | |
| SCHEMBL4337913 | 0.82 | PPARA (0.47) | L3MBTL1TGM2MAPK14THRBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |