SCHEMBL4335280

SCHEMBL4335280

CC(C)COc1ccccc1COC(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FOS P01100 2/20 0.45
JUN P05412 2/20 0.45
MTNR1A P48039 3/20 0.40
MTNR1B P49286 3/20 0.40
CCR8 P51685 2/20 0.40
KCNH2 Q12809 2/20 0.40
CACNA1G O43497 4/20 0.39
CACNA1H O95180 3/20 0.39
CACNA1I Q9P0X4 3/20 0.39
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
ELANE P08246 1/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
KAT6A Q92794 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17942368 0.89 ALDH1A1 (0.45) FOSJUNCCR8KCNH2CACNA1G
SCHEMBL4343859 0.85 L3MBTL1 (0.47) ALDH1A1TSHRKDM4ELMNA
SCHEMBL4342986 0.83 FFAR4 (0.46) MTNR1AMTNR1BKCNH2ALDH1A1ELANE
SCHEMBL4342476 0.82 BCHE (0.42) ALDH1A1KDM4ELMNA
SCHEMBL6151614 0.82 HTR1A (0.51) ALDH1A1KDM4ELMNASMN1; SMN2
SCHEMBL4332062 0.81 PPARD (0.46) ALDH1A1TSHRELANEKDM4ELMNA
SCHEMBL6150724 0.80 FFAR1 (0.51) ALDH1A1LMNASMN1; SMN2
SCHEMBL1790169 0.79 ALDH1A1 (0.55) MTNR1AMTNR1BALDH1A1TSHRELANE
SCHEMBL3173908 0.79 MTNR1A (0.39) FOSJUNMTNR1AMTNR1BCCR8
SCHEMBL25352804 0.78 HTR1A (0.50) ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247734-B1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2022-08-31 EP disclosed
US-10370491-B2 Preparation of highly heat-resistant (co)polycarbonates by the transesterification method COVESTRO DEUTSCHLAND AG (DE) 2019-08-06 US disclosed
US-20170369642-A1 Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method COVESTRO DEUTSCHLAND AG (DE) 2017-12-28 US disclosed
EP-3247734-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD Covestro Deutschland AG (DE) 2017-11-29 EP disclosed
WO-2016116480-A1 PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD COVESTRO DEUTSCHLAND AG (DE) 2016-07-28 WO disclosed
US-20090117314-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD BAYER MATERIALSCIENCE AG (DE) 2009-05-07 US disclosed