SCHEMBL6151614

SCHEMBL6151614

O=C(OCc1ccccc1OCc1ccccc1)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.51
DRD2 P14416 2/20 0.51
PTGER1 P34995 5/20 0.49
PTGER4 P35408 5/20 0.49
PTGER3 P43115 5/20 0.49
PTGER2 P43116 5/20 0.49
HTT P42858 2/20 0.48
BRD4 O60885 1/20 0.48
ABCB1 P08183 3/20 0.47
FOLH1 Q04609 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
GFER P55789 1/20 0.46
HSD17B10 Q99714 1/20 0.46
GAA P10253 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25352804 0.96 HTR1A (0.50) HTR1ADRD2PTGER1PTGER4PTGER3
SCHEMBL3477609 0.89 HTR1A (0.59) HTR1ADRD2PTGER1PTGER4PTGER3
SCHEMBL4343859 0.85 L3MBTL1 (0.47) HTTMEN1KMT2AHSD17B10GAA
SCHEMBL6150724 0.83 FFAR1 (0.51) MEN1KMT2AGAAL3MBTL1ALDH1A1
SCHEMBL4342476 0.83 BCHE (0.42) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL3980718 0.83 HTR1A (0.59) HTR1ADRD2PTGER1PTGER4PTGER3
SCHEMBL697595 0.82 KMT2A (0.60) HTTMEN1KMT2AGFERHSD17B10
SCHEMBL4332062 0.82 PPARD (0.46) MEN1KMT2AL3MBTL1KDM4EALDH1A1
SCHEMBL4335280 0.82 FOS (0.45) KDM4EALDH1A1LMNASMN1; SMN2
SCHEMBL3420132 0.80 ALDH1A1 (0.66) HTR1ADRD2PTGER1PTGER4PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427770-B1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GEN ELECTRIC (US) 2005-01-19 EP disclosed
EP-1427770-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-06-16 EP disclosed
US-20030120025-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2003-06-26 US disclosed
WO-2003022905-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-03-20 WO disclosed
US-6525163-B1 Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels GENERAL ELECTRIC COMPANY 2003-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120025-A1 Process for the production of polycarbonate RNGTT, CAPG, RPL30 HTR1A 3066/4885DRD2 3410/4885PTGER1 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.