Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324640 | 0.82 | HCRTR1 (0.54) | CYP2C19CYP2C9SCN9AALDH1A1CNR2 | |
| SCHEMBL4320012 | 0.82 | LMNA (0.46) | CPT2CPT1ACPT1BSCN9AALDH1A1 | |
| SCHEMBL4333849 | 0.82 | DRD2 (0.46) | CPT2CPT1ACPT1BSCN9ANAMPT | |
| SCHEMBL4324654 | 0.81 | NPC1 (0.46) | CPT2CPT1ACPT1BSCN9ACNR2 | |
| SCHEMBL4319190 | 0.81 | SLC22A12 (0.43) | CPT2CPT1ACPT1BSCN9ASMYD2 | |
| SCHEMBL4336015 | 0.81 | NPC1 (0.41) | CYP2C19CYP2C9CPT2CPT1ACPT1B | |
| SCHEMBL4324512 | 0.81 | MEN1 (0.52) | SCN9AALDH1A1CNR2CNR1 | |
| SCHEMBL4336046 | 0.80 | LMNA (0.46) | SCN9AALDH1A1DRD2DRD3HTT | |
| SCHEMBL4326354 | 0.80 | NAMPT (0.46) | CPT2CPT1ACPT1BSCN9ASMYD2 | |
| SCHEMBL4324148 | 0.80 | SCN9A (0.46) | SCN9ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147121-A1 | CARBOXYL SUBSTITUTED INDOLES FOR USE AS PPAR ALPHA MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-10 | — | — | WO | disclosed |