Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 10/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337978 | 0.76 | LIMK1 (0.39) | ACVR1MAPK14ALDH1A1 | |
| SCHEMBL10411212 | 0.76 | — | — | |
| SCHEMBL16150637 | 0.75 | NOTUM (0.38) | ACVR1GSK3BPIM1ALDH1A1CYP1A2 | |
| SCHEMBL21351983 | 0.73 | — | — | |
| SCHEMBL5542129 | 0.73 | L3MBTL1 (0.43) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27996852 | 0.71 | TGFBR1 (0.49) | TGFBR1ALOX5APFEN1FLT3GSK3B | |
| SCHEMBL5535527 | 0.71 | ABL1 (0.42) | ALDH1A1 | |
| SCHEMBL8101802 | 0.71 | ADRA1A (0.34) | ALOX5APFEN1PIM1PIM2ALDH1A1 | |
| SCHEMBL9837227 | 0.70 | KDM4E (0.41) | TGFBR1ALDH1A1CYP1A2 | |
| SCHEMBL4190824 | 0.69 | PDPK1 (0.43) | TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035422-A1 | METHODS FOR INHIBITING BONE LOSS | ELI LILLY AND COMPANY (US) | 1996-11-14 | — | — | WO | disclosed |