Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21351983 | 0.86 | — | — | |
| SCHEMBL10411212 | 0.82 | — | — | |
| SCHEMBL8942364 | 0.76 | ADORA2A (0.32) | — | |
| SCHEMBL4337978 | 0.75 | LIMK1 (0.39) | LIMK1 | |
| SCHEMBL16150637 | 0.75 | NOTUM (0.38) | — | |
| SCHEMBL8101802 | 0.73 | ADRA1A (0.34) | — | |
| SCHEMBL9837227 | 0.72 | KDM4E (0.41) | — | |
| SCHEMBL9948647 | 0.71 | — | — | |
| SCHEMBL11200488 | 0.70 | — | — | |
| SCHEMBL7754182 | 0.70 | KDM4E (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272745-A1 | Novel piperidine and piperazine derivatives | ASTRAZENECA AB | 2005-12-08 | — | — | US | claimed |
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | claimed |
| US-20050272745-A1 | Novel piperidine and piperazine derivatives | ASTRAZENECA AB | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272745-A1 | Novel piperidine and piperazine derivatives | CYP3A5, IL5, ABCC5 | LIMK1 4544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.