SCHEMBL434000

SCHEMBL434000

CCOP(=S)(CC)Oc1cc(Cl)c(I)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPT P10636 3/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
MAPK1 P28482 1/20 0.36
ATM Q13315 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29494642 0.87 TDP1 (0.47) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL117717 0.87 TDP1 (0.47) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL1019913 0.86 TDP1 (0.46) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL27766412 0.84 TDP1 (0.60) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL11524034 0.78 TDP1 (0.40) TDP1MEN1KMT2AALDH1A1MAPT
SCHEMBL1275737 0.72 KCNH2 (0.40) TDP1MEN1KMT2AALDH1A1MAPT
Iodofenphos SCHEMBL11608297 0.72 TDP1 (0.44) TDP1MEN1KMT2AALDH1A1CYP3A4
Iodofenphos SCHEMBL7757435 0.72 TDP1 (0.44) TDP1MEN1KMT2AALDH1A1CYP3A4
Iodofenphos SCHEMBL39677 0.72 TDP1 (0.44) TDP1MEN1KMT2AALDH1A1CYP3A4
Iodofenphos SCHEMBL10532635 0.71 TDP1 (0.42) TDP1MEN1KMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2347655-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngenta Participations AG. (CH) 2011-07-27 EP claimed
EP-2332411-A1 Fungicidal compositions Syngenta Participations AG (CH) 2011-06-15 EP claimed
JP-2008509189-A 2008-03-27 JP claimed
US-20080076664-A1 Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. 2008-03-27 US claimed
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic SYNGENTA CROP PROTECTION, INC. (US) 2008-03-20 US claimed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US claimed
EP-1802198-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-07-04 EP claimed
EP-1796464-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-06-20 EP claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 EP claimed
WO-2006037632-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006037634-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006037633-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO claimed
EP-4098650-B1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT KUMIAI CHEMICAL INDUSTRY CO (JP) 2025-12-10 EP disclosed
US-20240208962-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 US disclosed
WO-2024132901-A1 MICROBIOCIDAL PYRIDAZINE DIHYDROOXADIAZINE DERIVATIVES SYNGENTA CROP PROTECTION AG (CH) 2024-06-27 WO disclosed
WO-2006032462-A1 NOVEL INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2006-03-30 WO disclosed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO disclosed
US-20050274059-A1 Pesticidal mixtures SYNGENTA CROP PROTECTION, INC. 2005-12-15 US disclosed
WO-2005107468-A1 PESTICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2005-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240208962-A1 MICROBIOCIDAL QUINOLINE/QUINOXALINE BENZOTHIAZINE DERIVATIVES IFNG, IRF3, MAVS TDP1 1041/4885MEN1 2116/4885KMT2A 2527/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 TDP1 1332/4885MEN1 337/4885KMT2A 2009/4885
US-20080070785-A1 For controlling phytopathogenic diseases; synergistic BROX, EPM2A, MANBA TDP1 2299/4885MEN1 927/4885KMT2A 3493/4885
US-20080076664-A1 Fungicidal Compositions AKR7A2, CYP51A1, TUBA3C TDP1 966/4885MEN1 300/4885KMT2A 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.