Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354113 | 0.85 | KDM4E (0.44) | DGAT1ALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL321094 | 0.74 | DGAT1 (0.66) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL31173096 | 0.72 | HPGD (0.50) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL29401981 | 0.71 | ALDH1A1 (0.52) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL181200 | 0.71 | ALDH1A1 (0.52) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL6862035 | 0.70 | FLT1 (0.46) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL257466 | 0.69 | FLT1 (0.49) | DGAT1ALDH1A1NPC1LMNAGAA | |
| SCHEMBL12198995 | 0.69 | ALOX5AP (0.45) | DGAT1ALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL30665731 | 0.69 | ALOX5AP (0.45) | DGAT1ALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL30526110 | 0.69 | FLT1 (0.49) | DGAT1ALDH1A1NPC1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544400-B2 | Bimesogenic compounds and flexoelectric devices | MERCK PATENT GMBH (DE) | 2009-06-09 | — | — | US | disclosed |
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MERCK PATENT GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| EP-1828345-B1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2008-05-14 | — | — | EP | disclosed |
| EP-1828345-A1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | Merck Patent GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006066688-A1 | BIMESOGENIC COMPOUNDS AND FLEXOELECTRIC DEVICES | MERCK PATENT GMBH (DE) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080142758-A1 | Bimesogenic Compounds And Flexoelectric Devices | MLX, FOXM1, SFXN1 | DGAT1 4596/4885ALDH1A1 4413/4885NPC1 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.