Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | AOC2 | O75106 | 5/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568271 | 0.81 | CA2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL21101519 | 0.80 | KDM4E (0.49) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL451210 | 0.80 | MAOB (0.41) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL6209606 | 0.80 | MAOB (0.41) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL28842254 | 0.80 | MAOB (0.49) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL12060988 | 0.80 | HRH3 (0.49) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL30142986 | 0.80 | HRH3 (0.49) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL334480 | 0.80 | HRH3 (0.49) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL10508395 | 0.79 | MAOA (0.42) | MAOAMAOBAOC2DAOCHRM2 | |
| SCHEMBL9113367 | 0.77 | HRH3 (0.40) | MAOAMAOBAOC2DAOCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181550-B1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER IP GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| US-10093611-B2 | Benzocycloalkenes as antifungal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-10-09 | — | — | US | disclosed |
| EP-2595961-B1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER IP GMBH (DE) | 2017-07-19 | — | — | EP | disclosed |
| EP-3181550-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2017-06-21 | — | — | EP | disclosed |
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-01-28 | — | — | US | disclosed |
| US-9173399-B2 | Benzocycloalkenes as antifungal agents | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| EP-2595961-A2 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | Bayer Intellectual Property GmbH (DE) | 2013-05-29 | — | — | EP | disclosed |
| US-20130123322-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-16 | — | — | US | disclosed |
| WO-2012010579-A2 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | BAYER CROPSCIENCE AG (DE) | 2012-01-26 | — | — | WO | disclosed |
| CN-1193020-C | Process for preparing amic acid esters | IHARA CHEMICAL IND CO (JP) | 2005-03-16 | — | — | CN | disclosed |
| US-20040127433-A1 | excellent antibacterial activity especially against a typical acid-fast mycobacteria including multiple drug-resistant bacteria | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1323726-A1 | ERYTHROMYCIN DERIVATIVES AND MEDICINES CONTAINING THE SAME | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6576765-B2 | Process for preparing amic acid esters | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| CN-1366523-A | Process for preparing amic acid esters | IHARA CHEMICAL IND CO (JP) | 2002-08-28 | — | — | CN | disclosed |
| EP-1182199-A1 | PROCESS FOR PREPARING AMIC ACID ESTERS | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127433-A1 | excellent antibacterial activity especially against a typical acid-fast mycobacteria including multiple drug-resistant bacteria | MAPRE1, MAPRE2, MRPS27 | MAOA 1796/4885MAOB 1680/4885AOC2 373/4885 |
| US-20160023987-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | CYP51A1, ERG28, CBR1 | MAOA 1922/4885MAOB 1381/4885AOC2 116/4885 |
| US-10093611-B2 | Benzocycloalkenes as antifungal agents | CYP51A1, ERG28, CBR1 | MAOA 1922/4885MAOB 1381/4885AOC2 116/4885 |
| US-20130123322-A1 | BENZOCYCLOALKENES AS ANTIFUNGAL AGENTS | CYP51A1, ERG28, CBR1 | MAOA 1922/4885MAOB 1381/4885AOC2 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.