Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHAT | P28329 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028188 | 0.85 | SMPD2 (0.41) | SMPD2ALDH1A1F2LMNACHAT | |
| SCHEMBL5254370 | 0.82 | RXRA (0.41) | SMPD2ALDH1A1CHATMTNR1AMTNR1B | |
| SCHEMBL9859576 | 0.82 | SMPD2 (0.43) | SMPD2ALDH1A1F2LMNACHAT | |
| SCHEMBL6709451 | 0.80 | SMPD2 (0.53) | SMPD2ALDH1A1F2LMNAMTNR1A | |
| SCHEMBL133603 | 0.79 | CHAT (0.46) | ALDH1A1CHATMTNR1AMTNR1BKDM4E | |
| SCHEMBL8329887 | 0.75 | GRIK1 (0.44) | SMPD2KDM4ERXRAGRIN2DGRIN3B | |
| SCHEMBL9129455 | 0.75 | ACP3 (0.45) | SMPD2ALDH1A1F2LMNAKDM4E | |
| SCHEMBL108120 | 0.74 | CHAT (0.43) | ALDH1A1CHATMTNR1AMTNR1BKDM4E | |
| SCHEMBL10675341 | 0.74 | CYP1A2 (0.46) | SMPD2CHATMTNR1AMTNR1BKDM4E | |
| SCHEMBL7795350 | 0.74 | RXRA (0.43) | ALDH1A1CHATMTNR1AMTNR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358396-B2 | Preparation of optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-15 | — | — | US | disclosed |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | Source Global, PBC | 2007-07-05 | — | — | US | disclosed |
| US-7193092-B2 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7078226-B1 | Method for producing optically active amines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-18 | — | — | US | disclosed |
| US-20060122429-A1 | Preparation of optically active amines | DITRICH KLAUS | 2006-06-08 | — | — | US | disclosed |
| EP-1400527-B1 | Chiral diphosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| EP-1592683-A2 | HETEROCYCLYL-3-SULFONYLINDAZOLES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | Wyeth (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1398319-B1 | Chiral monophosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2005-11-09 | — | — | EP | disclosed |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2005-04-14 | — | — | US | disclosed |
| EP-1232279-B1 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AG (DE) | 2005-03-02 | — | — | EP | disclosed |
| EP-1398319-A1 | Chiral monophosphorus compounds and transition metal complexes thereof | Bayer Chemicals AG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1232279-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-08-21 | — | — | EP | disclosed |
| EP-1165515-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-02 | — | — | EP | disclosed |
| EP-0906324-B1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| WO-2001038292-A2 | METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-31 | — | — | WO | disclosed |
| WO-2000058288-A1 | PYRIDINE-2,3-DICARBOXYLIC ACID DIAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| US-5990320-A | Optically active diphosphine ligands | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
| EP-0906324-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| WO-1997045436-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122429-A1 | Preparation of optically active amines | MAOA, MAOB, NAAA | SMPD2 500/4885ALDH1A1 283/4885F2 2329/4885 |
| US-20070155971-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | SMPD2 4128/4885ALDH1A1 3235/4885F2 2341/4885 |
| US-20050080047-A1 | Chiral diphosphorus compounds and their transition metal complexes | CDIPT, DCPS, PIN1 | SMPD2 4128/4885ALDH1A1 3235/4885F2 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.