Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434387 | 0.77 | HRH3 (0.43) | PTGIRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL433443 | 0.75 | HRH3 (0.43) | PTGIRMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL432402 | 0.70 | GPR88 (0.48) | KDM4ESMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL10084055 | 0.70 | GPR88 (0.48) | KDM4ESMN1; SMN2ALDH1A1MAPK1GAA | |
| SCHEMBL10926912 | 0.68 | HTT (0.61) | LTA4HKDM4ESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8437918 | 0.68 | OPRM1 (0.51) | PTGIRKMT2AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL4931908 | 0.68 | HRH3 (0.53) | PTGIRKMT2ASMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL10923936 | 0.68 | RAB9A (0.61) | LTA4HKDM4ESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10922970 | 0.68 | RAB9A (0.61) | LTA4HKDM4ESMN1; SMN2ALDH1A1HTT | |
| Bromide SCHEMBL10553706 | 0.68 | HTT (0.60) | LTA4HKDM4ESMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |