Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433443 | 0.92 | HRH3 (0.43) | HRH3PTGIRKMT2AMEN1OPRM1 | |
| SCHEMBL434778 | 0.77 | PTGIR (0.44) | HRH3PTGIRKMT2AMEN1GAA | |
| SCHEMBL4931908 | 0.69 | HRH3 (0.53) | HRH3PTGIRKMT2AOPRM1SIGMAR1 | |
| SCHEMBL8437918 | 0.69 | OPRM1 (0.51) | HRH3PTGIRKMT2AOPRM1SIGMAR1 | |
| SCHEMBL15380628 | 0.69 | ALDH1A1 (0.44) | CYP2D6CYP2C9HIF1AKMT2AMEN1 | |
| SCHEMBL432280 | 0.69 | ALDH1A1 (0.44) | CYP2D6CYP2C9HIF1AKMT2AMEN1 | |
| SCHEMBL6209135 | 0.67 | PDK1 (0.47) | HRH3PTGIRKMT2AOPRM1SIGMAR1 | |
| SCHEMBL5758121 | 0.66 | ADRA2C (0.61) | PTGIRKMT2AALDH1A1GFERKDM4E | |
| SCHEMBL4233535 | 0.66 | PDK1 (0.49) | HRH3PTGIRKMT2AOPRM1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL5071191 | 0.66 | PDK1 (0.47) | HRH3PTGIRKMT2AMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | claimed |