Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350129 | 0.95 | KDM4E (0.37) | KDM4ESMN1; SMN2ALDH1A1CHRM5CHRM2 | |
| SCHEMBL4352065 | 0.92 | ALDH1A1 (0.39) | MAPK14KDM4ESMN1; SMN2ALDH1A1CHRM5 | |
| SCHEMBL4354023 | 0.91 | SMN1; SMN2 (0.44) | MAPK14KDM4ESMN1; SMN2ALDH1A1CHRM5 | |
| SCHEMBL4350015 | 0.91 | GPR119 (0.41) | KDM4ESMN1; SMN2ALDH1A1CHRM5CHRM2 | |
| SCHEMBL4353651 | 0.89 | KCNH2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL4353425 | 0.89 | SCD5 (0.36) | KDM4ESMN1; SMN2ALDH1A1GPR119 | |
| SCHEMBL4532899 | 0.88 | KDM4E (0.36) | KDM4ESMN1; SMN2ALDH1A1CHRM5CHRM2 | |
| SCHEMBL4349648 | 0.87 | ALDH1A1 (0.39) | KDM4ESMN1; SMN2ALDH1A1CHRM5CHRM2 | |
| SCHEMBL4532545 | 0.87 | GPR119 (0.46) | MAPK14KDM4ECD274GPR119 | |
| SCHEMBL4358687 | 0.86 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1CHRM5CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |