Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358687 | 0.95 | SMN1; SMN2 (0.46) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4348559 | 0.91 | MAPK14 (0.37) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4354226 | 0.91 | KDM4E (0.45) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4349657 | 0.91 | GPR119 (0.44) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4532545 | 0.90 | GPR119 (0.46) | KDM4EMAPK14 | |
| SCHEMBL4361277 | 0.89 | MAPK14 (0.40) | MAPK14LMNADRD2 | |
| SCHEMBL4354303 | 0.89 | KDM4E (0.43) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4356877 | 0.88 | ALDH1A1 (0.45) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4531625 | 0.88 | ALDH1A1 (0.40) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 | |
| SCHEMBL4352059 | 0.87 | P2RY12 (0.41) | SMN1; SMN2KDM4EALDH1A1CHRM5CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |