Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353651 | 0.92 | KCNH2 (0.38) | KCNH2HRH3ENPP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4350015 | 0.92 | GPR119 (0.41) | KCNH2HRH3GPR119P2RY12NPY2R | |
| SCHEMBL4522943 | 0.91 | ALDH1A1 (0.36) | GPR119KDM4EALDH1A1 | |
| SCHEMBL4534628 | 0.91 | GPR119 (0.40) | GPR119 | |
| SCHEMBL4531625 | 0.91 | ALDH1A1 (0.40) | SCD5SCDKCNH2HRH3P2RY12 | |
| SCHEMBL4350129 | 0.90 | KDM4E (0.37) | GPR119KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4352065 | 0.90 | ALDH1A1 (0.39) | P2RY12KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4352709 | 0.89 | HDAC1 (0.33) | GPR119ENPP2P2RY12 | |
| SCHEMBL4348559 | 0.89 | MAPK14 (0.37) | GPR119KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4532899 | 0.89 | KDM4E (0.36) | GPR119ENPP2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |