Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531957 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MAPK1RAB9ANPC1PKM | |
| SCHEMBL4350129 | 0.88 | KDM4E (0.37) | ALDH1A1RAB9AKDM4ECHRM5CHRM2 | |
| SCHEMBL13586064 | 0.88 | GPR119 (0.42) | ALDH1A1RAB9ANPC1PKMKDM4E | |
| SCHEMBL4352065 | 0.88 | ALDH1A1 (0.39) | ALDH1A1CYP2C9KDM4ECHRM5CHRM2 | |
| SCHEMBL4348559 | 0.87 | MAPK14 (0.37) | ALDH1A1KDM4ECHRM5CHRM2CHRM3 | |
| SCHEMBL4350015 | 0.87 | GPR119 (0.41) | ALDH1A1KDM4ECHRM5CHRM2CHRM3 | |
| SCHEMBL4541611 | 0.87 | RAB9A (0.39) | ALDH1A1RAB9ANPC1PKMCYP3A4 | |
| SCHEMBL4353651 | 0.85 | KCNH2 (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL4353425 | 0.85 | SCD5 (0.36) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4535777 | 0.85 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1PKMCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |