Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355702 | 0.83 | PIK3CA (0.37) | GPR119PIK3CAUSP30PTGS2CYP11B2 | |
| SCHEMBL4353588 | 0.82 | PIK3CA (0.43) | GPR119PIK3CAUSP30SLC6A9 | |
| SCHEMBL4535480 | 0.82 | LMNA (0.42) | GPR119PIK3CAUSP30CYP11B2 | |
| SCHEMBL4347925 | 0.82 | USP30 (0.40) | GPR119PIK3CAUSP30PTGS2DPP4 | |
| SCHEMBL4357301 | 0.81 | PIK3CA (0.35) | GPR119PIK3CAUSP30PTGS2 | |
| SCHEMBL4537918 | 0.81 | PTPN2 (0.43) | PIK3CACA12CA1CA2 | |
| SCHEMBL4356473 | 0.81 | PTPN2 (0.43) | PIK3CACA12CA1CA2 | |
| SCHEMBL4349922 | 0.81 | PTPN2 (0.43) | PIK3CACA12CA1CA2 | |
| SCHEMBL4356151 | 0.81 | GAA (0.42) | GPR119PIK3CARBP4 | |
| SCHEMBL4531447 | 0.80 | PIK3CA (0.44) | GPR119PIK3CAUSP30PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |