Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.38 |
| ▸ | TRPC7 | Q9HCX4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536272 | 0.91 | KMT2A (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19GPR119 | |
| SCHEMBL4533655 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2NPC1RAB9ACYP2C19GPR119 | |
| SCHEMBL4355143 | 0.85 | GPR119 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19GPR119 | |
| SCHEMBL4352115 | 0.84 | GPR119 (0.46) | SMN1; SMN2NPC1RAB9ACYP2C19GPR119 | |
| SCHEMBL4526460 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2NPC1RAB9ACYP2C19TRPC3 | |
| SCHEMBL4351624 | 0.82 | ENPP2 (0.44) | SMN1; SMN2NPC1RAB9ACYP2C19GPR119 | |
| SCHEMBL4520212 | 0.81 | PTPN2 (0.47) | SMN1; SMN2CYP2C19MEN1KMT2AHTR2B | |
| SCHEMBL4356808 | 0.81 | SETD7 (0.45) | CYP2C19GPR119MEN1KMT2ANPSR1 | |
| SCHEMBL4529914 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL4355595 | 0.79 | POLB (0.54) | SMN1; SMN2CYP2C19HTR2BCYP2C9PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |