Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352615 | 0.91 | POLB (0.39) | SETD7KMT2ACYP2C19MEN1GAA | |
| SCHEMBL4524446 | 0.90 | GPR119 (0.40) | SETD7KMT2ACYP2C19MEN1GAA | |
| SCHEMBL4355704 | 0.90 | RAB9A (0.46) | SETD7KMT2ACYP2C19MEN1GAA | |
| SCHEMBL4360439 | 0.89 | TSHR (0.44) | KMT2AMEN1GAAKDM4EHPGD | |
| SCHEMBL13586034 | 0.89 | ABL1 (0.46) | KMT2AMEN1POLBCNR2GPR119 | |
| SCHEMBL4357683 | 0.88 | POLB (0.48) | HPGDPOLBALDH1A1GPR119ROCK2 | |
| SCHEMBL4355595 | 0.88 | POLB (0.54) | CYP2C19HPGDPOLBALDH1A1LMNA | |
| SCHEMBL4534565 | 0.87 | KDM4E (0.40) | KMT2AGAAKDM4EHPGDALDH1A1 | |
| SCHEMBL4348683 | 0.87 | TNKS (0.41) | KMT2AMEN1NPSR1HTTLMNA | |
| SCHEMBL4531625 | 0.86 | ALDH1A1 (0.40) | GAAKDM4ENPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |