Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19215484 | 0.95 | ELANE (0.41) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL13604258 | 0.83 | PSIP1 (0.46) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL11793653 | 0.78 | TSHR (0.52) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL1130280 | 0.74 | MAPT (0.47) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL11156717 | 0.74 | TSHR (0.46) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL23094333 | 0.73 | TDP1 (0.52) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL11606202 | 0.73 | THRB (0.44) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19097597 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL29323751 | 0.72 | POLB (0.51) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL24390169 | 0.71 | HSD11B1 (0.46) | POLBAPEX1HTTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090033859-A1 | Liquid Crystal Spacer, Spacer Diffusion Liquid, Liquid Crystal Display Device Manufacturing Method, and Liquid Crystal Display Device | SEKISUI CHEMICAL CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-7291393-B2 | Coated conductive particle coated conductive particle manufacturing method anisotropic conductive material and conductive connection structure | SEKISUI CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20060154070-A1 | Coated conductive particle coated conductive particle manufacturing method anisotropic conductive material and conductive connection structure | SEKISUI CHEMICAL CO., LTD. (JP) | 2006-07-13 | — | — | US | disclosed |
| EP-1426979-A1 | COATED CONDUCTIVE PARTICLE, COATED CONDUCTIVE PARTICLE MANUFACTURING METHOD, ANISOTROPIC CONDUCTIVE MATERIAL, AND CONDUCTIVE CONNECTION STRUCTURE | SEKISUI CHEMICAL CO., LTD. (JP) | 2004-06-09 | — | — | EP | disclosed |