Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354311 | 0.93 | GPR119 (0.44) | GPR119CRBNDYRK2STAT3HDAC4 | |
| SCHEMBL4347903 | 0.89 | GPR119 (0.44) | GPR119HRH3 | |
| SCHEMBL4525904 | 0.89 | HRH3 (0.40) | GPR119HRH3STAT3 | |
| SCHEMBL4352666 | 0.87 | GPR119 (0.49) | GPR119DYRK2 | |
| SCHEMBL4536512 | 0.86 | GPR119 (0.47) | GPR119 | |
| SCHEMBL4355704 | 0.84 | RAB9A (0.46) | HRH3STAT3 | |
| SCHEMBL13586034 | 0.83 | ABL1 (0.46) | GPR119CRBNHDAC4 | |
| SCHEMBL4352054 | 0.82 | GPR119 (0.46) | GPR119 | |
| SCHEMBL4536116 | 0.81 | STAT3 (0.43) | HRH3STAT3 | |
| SCHEMBL13586046 | 0.80 | GPR119 (0.57) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |