Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536116 | 0.91 | STAT3 (0.43) | HRH3STAT3BMPR1BBMPR1AACVRL1 | |
| SCHEMBL4351360 | 0.89 | GPR119 (0.42) | HRH3STAT3GPR119 | |
| SCHEMBL4351323 | 0.88 | HRH3 (0.45) | HRH3ALDH1A1 | |
| SCHEMBL4350001 | 0.85 | SLC6A7 (0.46) | ALDH1A1 | |
| SCHEMBL4355704 | 0.82 | RAB9A (0.46) | HRH3STAT3ALDH1A1POLB | |
| SCHEMBL4532442 | 0.81 | STAT3 (0.43) | HRH3STAT3BMPR1BBMPR1AACVRL1 | |
| SCHEMBL4357683 | 0.80 | POLB (0.48) | BMPR1BBMPR1AACVRL1ACVR1TNKS | |
| SCHEMBL4354311 | 0.80 | GPR119 (0.44) | STAT3GPR119 | |
| SCHEMBL4354257 | 0.80 | ROCK2 (0.40) | GPR119PIK3CAMTOR | |
| SCHEMBL4355713 | 0.80 | SLC6A7 (0.44) | STAT3ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |