Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351323 | 0.91 | HRH3 (0.45) | HRH3MKNK1MKNK2GRM5HPGD | |
| SCHEMBL4525904 | 0.91 | HRH3 (0.40) | STAT3HRH3BMPR1BBMPR1AACVRL1 | |
| SCHEMBL4532442 | 0.90 | STAT3 (0.43) | STAT3HRH3ROCK2MKNK1MKNK2 | |
| SCHEMBL4350001 | 0.89 | SLC6A7 (0.46) | — | |
| SCHEMBL4355704 | 0.89 | RAB9A (0.46) | STAT3HRH3ROCK2FLT3TYRO3 | |
| SCHEMBL4357683 | 0.89 | POLB (0.48) | ROCK2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL4354311 | 0.88 | GPR119 (0.44) | STAT3ROCK2 | |
| SCHEMBL4355713 | 0.88 | SLC6A7 (0.44) | STAT3 | |
| SCHEMBL4538191 | 0.85 | TNKS (0.41) | ROCK2BMPR1BBMPR1AACVRL1ACVR1 | |
| SCHEMBL4355595 | 0.83 | POLB (0.54) | POLBGRM5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |