Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AQP1 | P29972 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927659 | 0.89 | NISCH (0.40) | RAB9ATP53KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL17514748 | 0.86 | NISCH (0.41) | AHRRAB9ATP53KDM4ENPC1 | |
| SCHEMBL435603 | 0.86 | KMO (0.35) | HSD11B1 | |
| SCHEMBL435005 | 0.85 | AHR (0.45) | AHRRAB9ATP53KDM4ENPC1 | |
| SCHEMBL9138237 | 0.80 | HSD11B1 (0.41) | RAB9ATP53NPC1SMN1; SMN2HSD11B1 | |
| SCHEMBL9648679 | 0.79 | L3MBTL1 (0.40) | KDM4EMAPT | |
| SCHEMBL8527936 | 0.79 | HSD11B1 (0.43) | AHRRAB9ATP53KDM4ENPC1 | |
| SCHEMBL436469 | 0.76 | NOTUM (0.38) | AHRRAB9ATP53NPC1SMN1; SMN2 | |
| SCHEMBL434555 | 0.75 | CNR1 (0.34) | RAB9ATP53KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9598658 | 0.75 | AHR (0.37) | AHRRAB9ATP53NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |
| US-4530922-A | Fungicidal imidazoles and triazoles containing silicon | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-07-23 | — | — | US | disclosed |