SCHEMBL435290

SCHEMBL435290

N[C@@H](CCC(=O)O)C(=O)OC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 1/20 0.58
GRM6 O15303 1/20 0.58
GRIN2D O15399 1/20 0.58
GRIN3B O60391 1/20 0.58
GSR P00390 1/20 0.58
CYP1A2 P05177 1/20 0.58
GRIK1 P39086 1/20 0.58
GRM5 P41594 1/20 0.58
GRIA1 P42261 1/20 0.58
GRIA2 P42262 1/20 0.58
GRIA3 P42263 1/20 0.58
SLC1A3 P43003 1/20 0.58
SLC1A2 P43004 1/20 0.58
SLC1A1 P43005 1/20 0.58
GRIA4 P48058 1/20 0.58
GRIN1 Q05586 1/20 0.58
GRIN2A Q12879 1/20 0.58
GRIK2 Q13002 1/20 0.58
GRIK3 Q13003 1/20 0.58
GRIN2B Q13224 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2917215 1.00 GRM8 (0.58) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL496858 0.91 GRM8 (0.62) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL4959221 0.91 GRM8 (0.62) GRM8GRM6GRIN2DGRIN3BGSR
Hydrochloric Acid SCHEMBL10636419 0.89 GRM8 (0.60) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL22612661 0.88 ENPEP (0.47) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL27574633 0.86 ENPEP (0.48) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL435288 0.85 SLC1A1 (0.40) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL690872 0.85 GRM8 (0.56) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL14125401 0.85 GRM8 (0.56) GRM8GRM6GRIN2DGRIN3BGSR
SCHEMBL20568580 0.85 GRM8 (0.56) GRM8GRM6GRIN2DGRIN3BGSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3827076-A1 IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF Uniwersytet Jagiellonski (PL) 2021-06-02 EP claimed
WO-2020021312-A1 IN VIVO DELIVERY SYSTEM OF THE GENOME DNA MODIFYING ENZYMES AND THE USE THEREOF UNIWERSYTET JAGIELLONSKI (PL) 2020-01-30 WO claimed
EP-1406930-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORPORATION (US) 2004-04-14 EP claimed
US-20040001822-A1 Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
US-20040002450-A1 Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
US-20040001839-A1 Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US claimed
WO-2002053700-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORP. (US) 2002-07-11 WO claimed
WO-2026090578-A1 CDH17-BINDING ANTIBODIES AND METHODS OF USE THEREOF Antharis Therapeutics Inc. (US) 2026-04-30 WO disclosed
EP-4731651-A1 DUAL TRANSPORTERS AND METHODS OF USE Denali Therapeutics Inc. (US) 2026-04-29 EP disclosed
EP-4724458-A2 PEPTIDE THERAPEUTICS The Regents of the University of California (US) 2026-04-15 EP disclosed
EP-4720114-A2 ANTI-HBSAG ANTIBODY FOR TREATMENT OF CHRONIC HEPATITIS D Bluejay Therapeutics, Inc. (US) 2026-04-08 EP disclosed
EP-4688805-A1 CYCLIC D-PEPTIDES, DERIVATIVES, COMPOSITIONS AND USES THEREOF Immune System Key Ltd. (IL) 2026-02-11 EP disclosed
WO-2025262082-A1 UNIVERSAL PRINCIPLES OF ACTIVE AND PASSIVE IMMUNIZATION AGAINST VIRAL ANTIGENS HEIDELBERG BIOTECH GMBH (DE) 2025-12-26 WO disclosed
EP-1406930-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORPORATION (US) 2004-04-14 EP disclosed
US-20040002450-A1 Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US disclosed
US-20040001822-A1 Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US disclosed
US-20040001839-A1 Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof BIO-TECHNOLOGY GENERAL (ISRAEL) LTD. (IL) 2004-01-01 US disclosed
EP-1363920-A1 MODIFIED PSMA LIGANDS AND USES RELATED THERETO Beth Israel Deaconess Medical Center (US) 2003-11-26 EP disclosed
WO-2002098885-A1 MODIFIED PSMA LIGANDS AND USES RELATED THERETO BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2002-12-12 WO disclosed
WO-2002053700-A2 ISOLATED MOLECULES COMPRISING EPITOPES CONTAINING SULFATED MOIETIES, ANTIBODIES TO SUCH EPITOPES, AND USES THEREOF BIO-TECHNOLOGY GENERAL CORP. (US) 2002-07-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040001822-A1 Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD47, CD14, SELE GRM8 4109/4885GRM6 3332/4885GRIN2D 4788/4885
US-20040001839-A1 Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD44, SELE, CD47 GRM8 3734/4885GRM6 2902/4885GRIN2D 4810/4885
US-20040002450-A1 Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof CD47, CD14, SELP GRM8 3632/4885GRM6 3668/4885GRIN2D 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.