Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586044 | 0.91 | ALDH1A1 (0.37) | GPR119ABL1MEN1KMT2AP2RY12 | |
| SCHEMBL4353425 | 0.89 | SCD5 (0.36) | GPR119ENPP2P2RY12 | |
| SCHEMBL13586062 | 0.88 | PTPN2 (0.44) | HDAC1HDAC2GPR119ABL1PTPN2 | |
| SCHEMBL4350129 | 0.88 | KDM4E (0.37) | GPR119 | |
| SCHEMBL4350015 | 0.88 | GPR119 (0.41) | HDAC1HDAC2GPR119MEN1KMT2A | |
| SCHEMBL4353651 | 0.88 | KCNH2 (0.38) | MEN1KMT2AENPP2 | |
| SCHEMBL4522943 | 0.86 | ALDH1A1 (0.36) | HDAC1HDAC2GPR119MEN1KMT2A | |
| SCHEMBL4534628 | 0.86 | GPR119 (0.40) | GPR119 | |
| SCHEMBL4531783 | 0.86 | ABL1 (0.34) | GPR119ABL1KMT2A | |
| SCHEMBL4348559 | 0.86 | MAPK14 (0.37) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |