Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534628 | 0.91 | GPR119 (0.40) | GPR119TSHR | |
| SCHEMBL4353425 | 0.91 | SCD5 (0.36) | ALDH1A1GPR119KDM4E | |
| SCHEMBL4534565 | 0.90 | KDM4E (0.40) | ALDH1A1GPR119HPGDMAPTTHRB | |
| SCHEMBL4350015 | 0.89 | GPR119 (0.41) | ALDH1A1GPR119MEN1KMT2AHDAC1 | |
| SCHEMBL4353651 | 0.89 | KCNH2 (0.38) | ALDH1A1RAB9AHPGDMAPTMEN1 | |
| SCHEMBL4352065 | 0.89 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL4356470 | 0.88 | GPR119 (0.38) | GPR119MEN1KMT2A | |
| SCHEMBL4352615 | 0.88 | POLB (0.39) | GPR119HPGDMEN1KMT2AROCK2 | |
| SCHEMBL4350129 | 0.88 | KDM4E (0.37) | ALDH1A1RAB9AGPR119KDM4E | |
| SCHEMBL4348559 | 0.86 | MAPK14 (0.37) | ALDH1A1GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |