Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 6/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522943 | 0.91 | ALDH1A1 (0.36) | GPR119TSHR | |
| SCHEMBL4353425 | 0.91 | SCD5 (0.36) | GPR119 | |
| SCHEMBL4360439 | 0.90 | TSHR (0.44) | GPR119TSHRCHRM2 | |
| SCHEMBL4352615 | 0.90 | POLB (0.39) | GPR119 | |
| SCHEMBL4356470 | 0.90 | GPR119 (0.38) | GPR119 | |
| SCHEMBL4350015 | 0.89 | GPR119 (0.41) | GPR119CHRM2 | |
| SCHEMBL4353651 | 0.89 | KCNH2 (0.38) | — | |
| SCHEMBL4350129 | 0.88 | KDM4E (0.37) | GPR119CHRM2 | |
| SCHEMBL4352065 | 0.87 | ALDH1A1 (0.39) | CHRM2 | |
| SCHEMBL4348559 | 0.86 | MAPK14 (0.37) | GPR119CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |