Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540460 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2NR3C1MTORGRM5NPC1 | |
| SCHEMBL4521195 | 0.89 | GPR119 (0.42) | SMN1; SMN2NR3C1 | |
| SCHEMBL4538191 | 0.82 | TNKS (0.41) | SMN1; SMN2MTORKCNH2NPC1RAB9A | |
| SCHEMBL4355344 | 0.81 | GPR119 (0.43) | TP53 | |
| SCHEMBL4362448 | 0.81 | TNKS (0.44) | SMN1; SMN2MTORKCNH2NPC1RAB9A | |
| SCHEMBL4355462 | 0.80 | POLB (0.42) | SMN1; SMN2KCNH2NPC1RAB9APIK3CA | |
| SCHEMBL4355330 | 0.78 | GPR119 (0.39) | MTORPIK3CA | |
| SCHEMBL4348683 | 0.78 | TNKS (0.41) | SMN1; SMN2MTORNPC1RAB9APIK3CA | |
| SCHEMBL4351738 | 0.78 | TNKS (0.38) | SMN1; SMN2MTORKCNH2NPC1RAB9A | |
| SCHEMBL13586038 | 0.77 | GPR119 (0.54) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |