Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538191 | 0.91 | TNKS (0.41) | SMN1; SMN2HTR2BNPC1RAB9AKDM4E | |
| SCHEMBL4353573 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2GRM5NPC1RAB9ATP53 | |
| SCHEMBL4521195 | 0.88 | GPR119 (0.42) | SMN1; SMN2NR3C1 | |
| SCHEMBL4533028 | 0.86 | HPGD (0.41) | HPGDALDH1A1PIK3CA | |
| SCHEMBL4351323 | 0.85 | HRH3 (0.45) | SMN1; SMN2GRM5RAB9AHPGDKDM4E | |
| SCHEMBL4355462 | 0.83 | POLB (0.42) | SMN1; SMN2HTR2BNPC1RAB9AKDM4E | |
| SCHEMBL4362448 | 0.81 | TNKS (0.44) | SMN1; SMN2HTR2BNPC1RAB9AMTOR | |
| SCHEMBL4356487 | 0.81 | ROCK2 (0.36) | MTORPIK3CA | |
| SCHEMBL4355330 | 0.80 | GPR119 (0.39) | HTR2BMTORSLC8A1PIK3CA | |
| SCHEMBL4348683 | 0.80 | TNKS (0.41) | SMN1; SMN2HTR2BNPC1RAB9AMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |