Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348683 | 0.90 | TNKS (0.41) | TNKSPDE7AHTR2BMTORPIK3CA | |
| SCHEMBL4355344 | 0.89 | GPR119 (0.43) | GPR119TNKS | |
| SCHEMBL4538191 | 0.89 | TNKS (0.41) | GPR119TNKSPDE7AHTR2BMTOR | |
| SCHEMBL4355462 | 0.87 | POLB (0.42) | TNKSGSK3BDYRK1AHTR2BPIK3CA | |
| SCHEMBL4362448 | 0.86 | TNKS (0.44) | TNKSPDE7AHTR2BMTORROCK2 | |
| SCHEMBL4351738 | 0.86 | TNKS (0.38) | GPR119TNKSPDE7AHTR2BMTOR | |
| SCHEMBL4521195 | 0.82 | GPR119 (0.42) | GPR119 | |
| SCHEMBL4540460 | 0.80 | SMN1; SMN2 (0.43) | HTR2BMTORPIK3CASLC8A1 | |
| SCHEMBL13586038 | 0.79 | GPR119 (0.54) | GPR119 | |
| SCHEMBL4353423 | 0.79 | PIK3CA (0.38) | GPR119PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |