Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355330 | 0.90 | GPR119 (0.39) | TNKSHTR2BPDE7AMTORPIK3CA | |
| SCHEMBL4355344 | 0.89 | GPR119 (0.43) | TNKSLMNA | |
| SCHEMBL4538191 | 0.89 | TNKS (0.41) | TNKSSMN1; SMN2L3MBTL1RAB9ANPC1 | |
| SCHEMBL4351738 | 0.88 | TNKS (0.38) | TNKSSMN1; SMN2RAB9ANPC1HTR2B | |
| SCHEMBL4356808 | 0.87 | SETD7 (0.45) | LMNAHTTMEN1KMT2ANPSR1 | |
| SCHEMBL4355462 | 0.87 | POLB (0.42) | TNKSSMN1; SMN2RAB9ANPC1HTR2B | |
| SCHEMBL4362448 | 0.86 | TNKS (0.44) | TNKSSMN1; SMN2RAB9ANPC1HTR2B | |
| SCHEMBL4355704 | 0.86 | RAB9A (0.46) | RAB9AMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL4521195 | 0.82 | GPR119 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL4540460 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1HTR2BMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |