Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 3/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538191 | 0.90 | TNKS (0.41) | TNKSHTR2BMTORNPC1RAB9A | |
| SCHEMBL4355462 | 0.88 | POLB (0.42) | TNKSHTR2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4348683 | 0.86 | TNKS (0.41) | TNKSHTR2BMTORNPC1RAB9A | |
| SCHEMBL4355330 | 0.86 | GPR119 (0.39) | TNKSHTR2BMTORPDE7AROCK2 | |
| SCHEMBL4351738 | 0.86 | TNKS (0.38) | TNKSFLT3HTR2BMTORNPC1 | |
| SCHEMBL4355344 | 0.86 | GPR119 (0.43) | TNKSCFTR | |
| SCHEMBL4532442 | 0.85 | STAT3 (0.43) | FLT3ROCK2BMPR1BBMPR1AACVRL1 | |
| SCHEMBL4540460 | 0.81 | SMN1; SMN2 (0.43) | HTR2BMTORNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4353573 | 0.81 | SMN1; SMN2 (0.41) | MTORNPC1RAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL4521195 | 0.78 | GPR119 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |