Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521195 | 0.93 | GPR119 (0.42) | GPR119SCD5LMNAPTPN2PTPN1 | |
| SCHEMBL13586038 | 0.90 | GPR119 (0.54) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4348683 | 0.89 | TNKS (0.41) | LMNATNKS | |
| SCHEMBL4355330 | 0.89 | GPR119 (0.39) | GPR119TNKS | |
| SCHEMBL4538191 | 0.88 | TNKS (0.41) | GPR119SCD5TNKS | |
| SCHEMBL13586034 | 0.88 | ABL1 (0.46) | GPR119TP53SCD5THRBRXFP1 | |
| SCHEMBL4354311 | 0.86 | GPR119 (0.44) | GPR119TP53THRBRXFP1LMNA | |
| SCHEMBL4355462 | 0.86 | POLB (0.42) | PTPN2PTPN1TNKS | |
| SCHEMBL4362448 | 0.86 | TNKS (0.44) | TNKSCFTR | |
| SCHEMBL4349923 | 0.84 | GPR119 (0.44) | GPR119PTPN2PTPN1PTPN6USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |