Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.36 |
| ▸ | DRD3 | P35462 | 6/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533473 | 0.95 | LMNA (0.40) | CD274SLC6A2SLC6A4NAMPTLMNA | |
| SCHEMBL4541177 | 0.91 | LMNA (0.45) | MAPK14SLC6A2SLC6A4NAMPTDRD2 | |
| SCHEMBL4354023 | 0.89 | SMN1; SMN2 (0.44) | MAPK14DRD2LMNA | |
| SCHEMBL4540129 | 0.89 | ALDH1A1 (0.43) | MAPK14CD274NAMPTDRD2DRD3 | |
| SCHEMBL4538002 | 0.88 | NPY2R (0.42) | MAPK14CD274SLC6A4NAMPT | |
| SCHEMBL4350134 | 0.88 | CD274 (0.36) | CD274SLC6A2SLC6A4NAMPTLMNA | |
| SCHEMBL4532545 | 0.88 | GPR119 (0.46) | MAPK14CD274NAMPT | |
| SCHEMBL4533472 | 0.86 | KMT2A (0.44) | SLC6A4DRD2DRD3 | |
| SCHEMBL4530802 | 0.86 | LMNA (0.51) | CD274SLC6A2SLC6A4LMNA | |
| SCHEMBL4360517 | 0.86 | NAMPT (0.41) | CD274NAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |