Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358687 | 0.92 | SMN1; SMN2 (0.46) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4349657 | 0.91 | GPR119 (0.44) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4352065 | 0.91 | ALDH1A1 (0.39) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4354023 | 0.91 | SMN1; SMN2 (0.44) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4540129 | 0.91 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NAMPTKMT2AMEN1 | |
| SCHEMBL4529951 | 0.90 | GPR119 (0.46) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL4354303 | 0.90 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4356877 | 0.89 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4531625 | 0.89 | ALDH1A1 (0.40) | KDM4EALDH1A1SMN1; SMN2CHRM5CHRM2 | |
| SCHEMBL4534565 | 0.88 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |