Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4531625 | 0.91 | ALDH1A1 (0.40) | ALDH1A1NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4353651 | 0.91 | KCNH2 (0.38) | ALDH1A1HSD17B10NPSR1TP53HPGD | |
| SCHEMBL4349657 | 0.90 | GPR119 (0.44) | ALDH1A1NPSR1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4358687 | 0.90 | SMN1; SMN2 (0.46) | ALDH1A1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4354226 | 0.89 | KDM4E (0.45) | ALDH1A1HPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4356930 | 0.89 | HDAC4 (0.50) | — | |
| SCHEMBL4534565 | 0.88 | KDM4E (0.40) | ALDH1A1HSD17B10TP53HPGDMAPT | |
| SCHEMBL4354023 | 0.88 | SMN1; SMN2 (0.44) | ALDH1A1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4360439 | 0.88 | TSHR (0.44) | ALDH1A1HSD17B10NPSR1HPGDMAPT | |
| SCHEMBL4533472 | 0.87 | KMT2A (0.44) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |