Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214539 | 0.90 | CYP2A6 (0.52) | CYP2A6AKR1B1MEN1KMT2ARXFP1 | |
| SCHEMBL7845940 | 0.89 | ERN1 (0.50) | CYP2A6MEN1KMT2ARXFP1MAPK14 | |
| SCHEMBL19871768 | 0.88 | ERN1 (0.46) | CYP2A6AKR1B1MEN1KMT2ARXFP1 | |
| SCHEMBL4354069 | 0.87 | CYP2A6 (0.65) | CYP2A6MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL18646836 | 0.85 | HPRT1 (0.64) | CYP2A6MEN1KMT2ARXFP1ALDH1A1 | |
| SCHEMBL11179246 | 0.83 | MEN1 (0.49) | CYP2A6AKR1B1MEN1KMT2ARXFP1 | |
| SCHEMBL9765502 | 0.80 | ALDH1A1 (0.52) | CYP2A6AKR1B1MAPK14ALDH1A1HSD17B10 | |
| SCHEMBL268735 | 0.80 | ALDH1A1 (0.65) | CYP2A6AKR1B1MAPK14ALDH1A1HSD17B10 | |
| SCHEMBL30186719 | 0.80 | ALDH1A1 (0.65) | CYP2A6AKR1B1MAPK14ALDH1A1HSD17B10 | |
| SCHEMBL29391827 | 0.80 | ALDH1A1 (0.65) | CYP2A6AKR1B1MAPK14ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10693077-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2020-06-23 | — | — | US | disclosed |
| US-10483468-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-19 | — | — | US | disclosed |
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| US-10454039-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-22 | — | — | US | disclosed |
| US-10454039-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-22 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-10431751-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-10-01 | — | — | US | disclosed |
| US-10424744-B2 | Compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-09-24 | — | — | US | disclosed |
| US-20170279050-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2017-09-28 | — | — | US | disclosed |
| US-20170213971-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
| US-20170213970-A1 | Novel compound and organic electronic device comprising the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2017-07-27 | — | — | US | disclosed |
| US-20170213978-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2017-07-27 | — | — | US | disclosed |
| US-5492917-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE, ANTIISCHEMIC,ANTISHOCK, ANTIINFLAMMATORY, ANTIALLERGEN AGENTS | MERCK & CO., INC. (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0319073-B1 | Cyclo-octane neuroprotective agents | MERCK SHARP & DOHME (GB) | 1995-08-23 | — | — | EP | disclosed |
| WO-1995008989-A1 | ENDOTHELIN ANTAGONISTS INCORPORATING A CYCLOBUTANE | MERCK & CO., INC. (US) | 1995-04-06 | — | — | WO | disclosed |
| EP-0272621-B1 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0319073-A2 | Cyclo-octane neuroprotective agents | MERCK SHARP & DOHME LTD. (GB) | 1989-06-07 | — | — | EP | disclosed |
| EP-0272621-A2 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1988-06-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10424744-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 518/4885AKR1B1 1834/4885MEN1 305/4885 |
| US-10693075-B2 | Spiro compound and organic electronic device comprising the same | ESRRA, REN, ESRRB | CYP2A6 632/4885AKR1B1 35/4885MEN1 2448/4885 |
| US-20170213978-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | OR51E2, OR10J3, ESR1 | CYP2A6 268/4885AKR1B1 2632/4885MEN1 481/4885 |
| US-10693077-B2 | Compound and organic electronic device using the same | SOD1, SCO2, RCOR3 | CYP2A6 1142/4885AKR1B1 496/4885MEN1 2385/4885 |
| US-20170279050-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | ESRRA, ESRRB, RCOR3 | CYP2A6 902/4885AKR1B1 387/4885MEN1 3217/4885 |
| US-10431751-B2 | Compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 518/4885AKR1B1 1834/4885MEN1 305/4885 |
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | CYP2A6 112/4885AKR1B1 1450/4885MEN1 205/4885 |
| US-20170213970-A1 | Novel compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 762/4885AKR1B1 1993/4885MEN1 251/4885 |
| US-20170213971-A1 | Novel compound and organic electronic device comprising the same | CHRM1, CHRM2, ESR1 | CYP2A6 762/4885AKR1B1 1993/4885MEN1 251/4885 |
| US-10454039-B2 | Compound and organic electronic device using the same | ORC3, AOX1, RCOR3 | CYP2A6 497/4885AKR1B1 447/4885MEN1 2797/4885 |
| US-10483468-B2 | Compound and organic electronic device using the same | ORC3, RBX1, CBX3 | CYP2A6 1506/4885AKR1B1 920/4885MEN1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.