SCHEMBL4354696

SCHEMBL4354696

ClC[SiH2]C(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.35
TSHR P16473 1/20 0.35
KCNA3 P22001 1/20 0.34
SLC6A4 P31645 1/20 0.34
PPARG P37231 9/20 0.34
PPARA Q07869 9/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
LMNA P02545 1/20 0.32
CA4 P22748 1/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
SCN4A P35499 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705838 0.82 LTA4H (0.38) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL704602 0.82 LTA4H (0.38) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL4361027 0.80 KCNA3 (0.39) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL705385 0.78 KCNA3 (0.39) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL704372 0.78 KCNA3 (0.39) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL4363429 0.78 KCNA3 (0.39) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL3359339 0.75 LTA4H (0.39) LTA4HTSHRKCNA3SLC6A4PPARG
SCHEMBL3815419 0.74 TAAR1 (0.41) LTA4HKCNA3
SCHEMBL4363261 0.72 KCNA3 (0.34) LTA4HTSHRKCNA3SLC6A4MTNR1A
SCHEMBL705003 0.68 CA1 (0.40) LTA4HTSHRKCNA3SLC6A4PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed