Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 10/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358302 | 0.88 | PIK3CA (0.42) | PIK3CAGPR119 | |
| SCHEMBL4356151 | 0.83 | GAA (0.42) | PIK3CAGPR119 | |
| SCHEMBL4535480 | 0.83 | LMNA (0.42) | PIK3CAGPR119USP30 | |
| SCHEMBL4353588 | 0.80 | PIK3CA (0.43) | PIK3CAGPR119USP30 | |
| SCHEMBL4347925 | 0.79 | USP30 (0.40) | PIK3CAGPR119USP30 | |
| SCHEMBL4355330 | 0.79 | GPR119 (0.39) | PIK3CAGPR119 | |
| SCHEMBL4349922 | 0.79 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4537918 | 0.79 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4356473 | 0.79 | PTPN2 (0.43) | PIK3CA | |
| SCHEMBL4348569 | 0.78 | GPR119 (0.39) | PIK3CAGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |