Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 3/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12041786 | 0.85 | SMN1; SMN2 (0.59) | MEN1KMT2AMAPTLMNAHTR1A | |
| SCHEMBL17207530 | 0.84 | POLB (0.65) | MEN1KMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL381655 | 0.83 | SMN1; SMN2 (0.58) | MEN1KMT2AMAPTLMNAHTR1A | |
| SCHEMBL8531897 | 0.81 | KCNH2 (0.58) | MEN1KMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL11214293 | 0.79 | HTR1A (0.56) | MEN1KMT2ATSHRLMNANPSR1 | |
| SCHEMBL10757967 | 0.79 | MEN1 (0.70) | MEN1KMT2ATSHRKCNH2HTR1A | |
| SCHEMBL8944148 | 0.78 | IGF1R (0.79) | MEN1KMT2ATSHRCYP1A2CYP3A4 | |
| Brl-15,572 SCHEMBL7741355 | 0.76 | MEN1 (1.00) | MEN1KMT2ATSHRCYP1A2CYP3A4 | |
| SCHEMBL10294634 | 0.76 | KCNH2 (0.69) | KCNH2 | |
| SCHEMBL5009485 | 0.76 | HTR1A (0.75) | MEN1KMT2ATSHRKCNH2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009105604-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | WO | disclosed |
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209550-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | HTR5A, HTR3A, HTR2C | MEN1 3990/4885KMT2A 4022/4885TSHR 268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.