Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 2/20 | 0.96 |
| ▸ | FEN1 | P39748 | 2/20 | 0.96 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HEXA | P06865 | 3/20 | 0.56 |
| ▸ | HEXB | P07686 | 3/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132760 | 0.98 | ERCC1 (1.00) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL29410043 | 0.98 | ERCC1 (1.00) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL27984890 | 0.96 | ERCC1 (0.96) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL4888025 | 0.96 | ERCC1 (0.96) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| Methane SCHEMBL20512282 | 0.96 | ERCC1 (0.96) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL65320 | 0.87 | ERCC1 (0.79) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL51719 | 0.82 | ERCC1 (0.71) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL7706742 | 0.81 | ERCC1 (0.70) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL7706718 | 0.81 | ERCC1 (0.70) | ERCC1FEN1ERCC4ALDH1A1KDM4E | |
| SCHEMBL7703367 | 0.81 | ERCC1 (0.70) | ERCC1FEN1ERCC4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213804-B2 | Dehydrogenation catalysts and methods of making and using the same | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-01-04 | — | — | US | disclosed |
| EP-3327003-B1 | PROCESS FOR CONCENTRATING A MIXTURE CONTAINING ORGANIC HYDROPEROXIDE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2020-09-16 | — | — | EP | disclosed |
| CN-106716252-B | Photosensitive resin composition, cured film and method for producing same, liquid crystal display device, organic electroluminescence display device, and touch panel | 富士胶片株式会社 | 2020-01-07 | — | — | CN | disclosed |
| CN-106687865-B | TFT substrate, organic EL display device, and method for manufacturing liquid crystal display device | 富士胶片株式会社 | 2020-01-03 | — | — | CN | disclosed |
| EP-3180304-B1 | PROCESS FOR PRODUCING CYCLOHEXANONE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-10-30 | — | — | EP | disclosed |
| US-20190283002-A1 | Dehydrogenation Catalysts and Methods of Making and Using the Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-09-19 | — | — | US | disclosed |
| EP-3013779-B1 | PROCESS FOR PRODUCING PHENOL AND/OR CYCLOHEXANONE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-07-31 | — | — | EP | disclosed |
| EP-3013795-B1 | PROCESS FOR CONCENTRATING A MIXTURE CONTAINING ORGANIC HYDROPEROXIDE | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-07-24 | — | — | EP | disclosed |
| US-10351506-B2 | Purified plasticizers, production and use | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190176131-A1 | Methods of Making Supported Mixed Metal Dehydrogenation Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-06-13 | — | — | US | disclosed |
| US-20020198135-A1 | Compositions for release of radiosensitizers, and methods of making and using the same | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE | 2002-12-26 | — | — | US | disclosed |
| WO-2002030472-A2 | COMPOSITIONS FOR RELEASE OF RADIOSENSITIZERS, AND METHODS OF MAKING AND USING THE SAME | GUILFORD PHARMACEUTICALS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |
| US-6358975-B1 | ADMINISTERING 3,4-DIHYDRO-5-(4-(1-PIPERIDINYL)-BUTOX)-1 (2H)-ISOQUINOLINONE, A SELECTIVE INHIBITOR OF POLY(ADP-RIBOSE) POLYMERASE FOR PROPHYLAXIS OF NEURAL TISSUE DAMAGE RESULTING FROM ISCHEMIA AND REPERFUSION INJURY OR NEURODEGENERATIVE | JOHNS HOPKINS UNIVERSITY | 2002-03-19 | — | — | US | disclosed |
| US-6348475-B1 | POLYMERASE INHIBITOR | GUILFORD PHARMACEUTICALS INC. | 2002-02-19 | — | — | US | disclosed |
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | EISAI INC. | 2002-02-14 | — | — | US | disclosed |
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| US-6242245-B1 | DELIGNIFICATION BY ADDING SUSPENSION OF LACCASE, OXIDANT, MEDIATOR SUCH AS VIOLURIC ACID, AND XYLANASE TO AQUEOUS SUSPENSION OF LIGNIN MATERIAL AND MIXING; MEDIATOR DOES NOT DEACTIVATE ENZYME | Consortium für elektrochemische Industrie GmbH (DE) | 2001-06-05 | — | — | US | disclosed |
| US-6187170-B1 | SYSTEM FOR THE ELECTROCHEMICAL CLEAVAGE OF COMPOUNDS WHICH INCLUDES A MEDIATOR AND AT LEAST TWO ELECTRODES FOR THE ELECTROCHEMICAL ACTIVATION OF THE MEDIATOR | Consortium für elektrochemische Industrie GmbH (DE) | 2001-02-13 | — | — | US | disclosed |
| US-6160128-A | Tritioacetylating reagents and processes for preparation thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-12-12 | — | — | US | disclosed |
| WO-1999008680-A1 | METHOD OF USING SELECTIVE PARP INHIBITORS TO PREVENT OR TREAT NEUROTOXICITY | THE JOHNS HOPKINS UNIVERSITY (US) | 1999-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213804-B2 | Dehydrogenation catalysts and methods of making and using the same | IDH2, ADH4, IDH1 | ERCC1 1492/4885FEN1 448/4885ERCC4 1146/4885 |
| US-10351506-B2 | Purified plasticizers, production and use | ALKBH3, FTO, ALK | ERCC1 625/4885FEN1 494/4885ERCC4 1069/4885 |
| US-20190176131-A1 | Methods of Making Supported Mixed Metal Dehydrogenation Catalysts | SOD1, DNMT1, CA1 | ERCC1 1224/4885FEN1 389/4885ERCC4 1144/4885 |
| US-20020198135-A1 | Compositions for release of radiosensitizers, and methods of making and using the same | XRCC6, MRE11, RAD51 | ERCC1 6/4885FEN1 263/4885ERCC4 13/4885 |
| US-20020019417-A1 | Methods, compounds and compositions for treating gout | PARP2, PARP1, PARP3 | ERCC1 139/4885FEN1 201/4885ERCC4 102/4885 |
| US-20190283002-A1 | Dehydrogenation Catalysts and Methods of Making and Using the Same | IDH2, ADH4, IDH1 | ERCC1 1492/4885FEN1 448/4885ERCC4 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.