Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.65 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.57 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.57 |
| ▸ | PRKDC | P78527 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4250883 | 0.99 | KMO (0.68) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL5743752 | 0.85 | ALDH1A1 (0.66) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL4203044 | 0.84 | ALDH1A1 (0.64) | ALOX15MAPTPKMMRGPRX4LMNA | |
| SCHEMBL8698430 | 0.83 | KMO (0.63) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL475555 | 0.83 | MRGPRX4 (0.54) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL1490676 | 0.82 | PLOD2 (0.60) | PLOD2PLOD3PLOD1LMNAALDH1A1 | |
| SCHEMBL30474594 | 0.82 | PLOD2 (0.67) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL28692105 | 0.82 | PLOD2 (0.67) | KMOALOX15MAPTPKMMRGPRX4 | |
| SCHEMBL13724478 | 0.82 | KMO (0.74) | KMOMAPTPLOD2PLOD3PLOD1 | |
| SCHEMBL1645102 | 0.82 | MRGPRX4 (0.60) | ALOX15MAPTPKMMRGPRX4PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541462-B2 | Triaminophosphine ligands for carbon-nitrogen and carbon-carbon bond formation | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080139806-A1 | TRIAMINOPHOSPHINE LIGANDS FOR CARBON-NITROGEN AND CARBON-CARBON BOND FORMATION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.. | 2008-06-12 | — | — | US | disclosed |
| US-7385058-B1 | Triaminophosphine ligands for carbon-nitrogen and carbon-carbon bond formation | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139806-A1 | TRIAMINOPHOSPHINE LIGANDS FOR CARBON-NITROGEN AND CARBON-CARBON BOND FORMATION | ABL1, AOC1, NPPA | KMO 3454/4885ALOX15 3967/4885MAPT 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.