Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21385706 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL8491250 | 0.82 | ALDH3A1 (0.51) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL1202449 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL18287474 | 0.79 | ALDH3A1 (0.53) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| Hydrogen Peroxide SCHEMBL28991385 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| Malonaldehyde SCHEMBL27607364 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL366474 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL28435633 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL2084156 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ARAB9ALMNA | |
| Lithium Ion SCHEMBL29035600 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1561474-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds of compositions for disinfection or sterilization | Ethicon, Inc. (US) | 2005-08-10 | — | — | EP | claimed |
| US-20050171201-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | claimed |
| US-7476767-B2 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | ETHICON, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7390837-B2 | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| EP-1561475-A1 | Germicidal compositions containing halogenated phthalaldehydes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1561478-A1 | Germicidal compositions containing phenylmalonaldehyde-type compounds and methods of using such compositions for disinfection or sterilization | ETHICON, INC. (US) | 2005-08-10 | — | — | EP | disclosed |
| EP-1561474-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds of compositions for disinfection or sterilization | Ethicon, Inc. (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050171216-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171215-A1 | Germicidal compositions containing halogenated phthalaldehyes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171121-A1 | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| US-20050171201-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | ETHICON, INC. | 2005-08-04 | — | — | US | disclosed |
| EP-1559435-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | Ethicon, Inc. (US) | 2005-08-03 | — | — | EP | disclosed |
| EP-1559704-A1 | Synthesis of 4-substituted phthalaldehyde | ETHICON, INC. (US) | 2005-08-03 | — | — | EP | disclosed |
| US-6891069-B1 | Synthesis of 4-substituted phthalaldehyde | ETHICON, INC. (US) | 2005-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171216-A1 | Germicidal compositions containing phthalaldehyde mixtures and methods of using such compositions for disinfection or sterilization | ALPG, DDT, DHODH | ALDH1A1 39/4885MAPT 2011/4885KMT2A 1763/4885 |
| US-20050171215-A1 | Germicidal compositions containing halogenated phthalaldehyes, and methods of using such compositions for disinfection or sterilization | ALPG, G6PD, PGLS | ALDH1A1 100/4885MAPT 1476/4885KMT2A 841/4885 |
| US-20050171201-A1 | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization | TST, STS, BPNT1 | ALDH1A1 7/4885MAPT 3752/4885KMT2A 2048/4885 |
| US-20050171121-A1 | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization | APEH, ALPG, DDT | ALDH1A1 17/4885MAPT 3629/4885KMT2A 1135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.