Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435967 | 0.83 | NR4A2 (0.38) | NR4A2BCHEACHESCN2AAURKA | |
| SCHEMBL22304001 | 0.76 | SCN2A (0.36) | NR4A2BCHEACHESCN2AAURKA | |
| SCHEMBL440378 | 0.73 | HAVCR2 (0.49) | AURKAAURKBHTTKMT2A | |
| SCHEMBL438876 | 0.71 | BCHE (0.43) | EPHB4BCHEACHESCN2APLAU | |
| SCHEMBL8057377 | 0.70 | NR4A2 (0.41) | NR4A2KMT2A | |
| SCHEMBL438598 | 0.70 | ACHE (0.41) | NR4A2ACHEHTTKMT2ACA1 | |
| SCHEMBL439299 | 0.68 | BCHE (0.34) | EPHB4BCHEACHEHTTKMT2A | |
| SCHEMBL436537 | 0.68 | NOS3 (0.38) | BCHEACHEHTTKMT2A | |
| SCHEMBL437551 | 0.68 | NR4A2 (0.51) | NR4A2BCHEACHE | |
| SCHEMBL18583152 | 0.67 | ALDH1A1 (0.37) | AURKAAURKBHTTADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065166-A1 | Bone Modulators And Methods Therewith | ESPINA VIRGINIA (US) | 2012-03-15 | — | — | US | disclosed |