SCHEMBL4359875

SCHEMBL4359875

N#CC1CCCCN1c1ccccc1N1CCOC1=O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.44
DPP7 Q9UHL4 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC9A3 P48764 1/20 0.35
PREP P48147 2/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
DPP4 P27487 2/20 0.33
UCHL1 P09936 1/20 0.33
MGLL Q99685 1/20 0.33
USP30 Q70CQ3 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2945343 0.74 UCHL1 (0.36) DPP4UCHL1USP30KDM4EMAPT
SCHEMBL3014037 0.73 KDM4E (0.39) ALDH1A1UCHL1USP30KDM4E
SCHEMBL7814732 0.73 KEAP1 (0.46) SLC9A3ALDH1A1GAAHSD17B10KMT2A
SCHEMBL7812796 0.73 FAAH (0.36) SLC9A3KMT2AKDM4E
SCHEMBL1843566 0.72 KEAP1 (0.49) SLC9A3ALDH1A1GAAHPGDHSD17B10
SCHEMBL2530053 0.71 GRM2 (0.45) SMN1; SMN2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL7823337 0.70 KEAP1 (0.42) SLC9A3ALDH1A1GAAHSD17B10KMT2A
SCHEMBL1660396 0.69 USP30 (0.50) ARDPP7SMN1; SMN2PREPDPP4
SCHEMBL5139359 0.68 PARP1 (0.38) SLC9A3KMT2AKDM4E
SCHEMBL31717769 0.68 DGAT1 (0.44) SLC9A3ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2072513-A1 A cyano piperidinyl-phenil-oxazolidinone and use thereof Ferrer Internacional, S.A. (ES) 2009-06-24 EP disclosed