Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945343 | 0.93 | UCHL1 (0.36) | KDM4EUSP30PIM1PIM3PIM2 | |
| SCHEMBL7814732 | 0.74 | KEAP1 (0.46) | ALDH1A1 | |
| SCHEMBL7823337 | 0.74 | KEAP1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL4359875 | 0.73 | AR (0.44) | KDM4EALDH1A1USP30UCHL1 | |
| SCHEMBL1843566 | 0.73 | KEAP1 (0.49) | ALDH1A1PIM1 | |
| SCHEMBL3584707 | 0.72 | ALOX15 (0.37) | KDM4EALDH1A1NOTUM | |
| SCHEMBL2530053 | 0.72 | GRM2 (0.45) | KDM4EALDH1A1NOTUMGRM2EGLN2 | |
| SCHEMBL6984223 | 0.71 | ADRB1 (0.49) | KDM4EALDH1A1PIM1PIM3PIM2 | |
| SCHEMBL7812796 | 0.69 | FAAH (0.36) | KDM4ENOTUM | |
| SCHEMBL138181 | 0.68 | KEAP1 (0.44) | KDM4ENOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112471-A | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | FERRER INT | 2011-06-29 | — | — | CN | disclosed |
| EP-2141161-A1 | 3-cyanopyrrolidinyl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2010-01-06 | — | — | EP | disclosed |